Alpha-2-macroglobulin as a Promising Biological Marker of Endothelial Function
نویسندگان
چکیده
منابع مشابه
Active MMPs captured by alpha 2 macroglobulin as a marker of disease activity in rheumatoid arthritis.
OBJECTIVE The aim of the present study was to analyze alpha 2 Macroglobulin/MMP (alpha 2M/MMP) complex formation and to investigate whether MMP activity in alpha 2M/MMP complexes in serum can be used as a disease marker in rheumatoid arthritis (RA). METHODS High and low molecular weight (H/LMW) substrates and inhibitors and size exclusion were used to analyze alpha 2M/MMP complex formation. L...
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Alpha macroglobulins are large glycoproteins which are present in the body fluids of both invertebrates and vertebrates. Alpha-2macroglobulin (a2M), a key member of alpha macroglobulin superfamily, is a high-molecular weight homotetrameric glycoprotein. a2Mhasmany diversified and complex functions, but it is primarily known by its ability to inhibit a broad spectrumof proteaseswithout the direc...
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ژورنال
عنوان ژورنال: Journal of Atherosclerosis and Thrombosis
سال: 2018
ISSN: 1340-3478,1880-3873
DOI: 10.5551/jat.41335